Maalox Stomach Pain Aluminum Hydroxide/Magnesium Hydroxide 400mg/400mg Chewable Tablet

· Intestinal absorption of aluminum hydroxide is low under normal conditions of use (see section 5.2). Prolonged use and/or excessive doses as well as use at the recommended doses in the context of a low phosphorus diet can lead to phosphorus depletion associated with increased bone resorption and hypercalciuria which may be the cause of osteomalacia. Aluminum hydroxide binds to phosphate in the gastrointestinal tract to form insoluble complexes thereby reducing phosphorus absorption. This medicine should be used with caution in people at risk of phosphorus depletion or in the event of prolonged treatment. A medical opinion is then recommended. In patients with renal insufficiency and chronic dialysis patients, take into account the content of aluminum and magnesium salts which may be increased in the plasma. Prolonged exposure to high doses may lead to a risk of encephalopathy, dementia, microcytic anemia or worsening of dialysis-induced osteomalacia. · Aluminum hydroxide may be dangerous in hemodialysis patients with porphyria. · In patients with renal impairment, the combination with citrates may lead to an increase in plasma aluminum levels (see section 4.5). In the event of persistence of the disorders beyond 10 days of treatment or aggravation of the disorders, an etiological search must be carried out and the action to be taken reassessed. · Prolonged use of antacids in renal insufficiency should be avoided.